Question 1

For which patient should you question the order for cyclobenzaprine (Flexeril)?

Accepted Answer

Cyclobenzaprine lowers the seizure threshold and can induce seizures.It should not be used in anyone who has epilepsy,which is a seizure disorder.It can cause severe hypertension but does not lower blood pressure.It can be used during pregnancy although the benefits versus the risks need to be considered.At the seventh month of pregnancy,the risk for birth defects is low (the highest risk is during the first trimester).

Question 2

Which electrolyte imbalance is most likely to trigger skeletal muscle spasms?

Accepted Answer

Calcium and magnesium are excitable membrane stabilizers.When either electrolyte is low,spontaneous depolarization of excitable membranes can occur,including those of nerves and skeletal muscles,resulting in skeletal muscle spasms.

Question 3

A patient who weighs 154 lb is prescribed to receive rasburicase (Elitek)0.2 mg/kg intravenously.The available drug has a concentration of 7.5 mg/mL.How many milliliters should you prepare to administer.

Accepted Answer

The answer of A patient who weighs 154 lb is...

Question 4

A patient is prescribed to receive methocarbamol 300 mg by direct intravenous push.The drug available is a 10% solution of 1000 mg/10 mL.How many milliliters will you prepare to administer?

Accepted Answer

The answer of A patient is prescribed to receive methocarbamol...

Question 5

A patient taking methocarbamol (Robaxin)for skeletal muscle cramping reports facial flushing.How should you respond?

Accepted Answer

Robaxin usually causes some facial flushing.This problem does not indicate any type of allergic response and does not require either stopping the drug or implementing an intervention.

Question 6

Which drugs belong to the estrogen agonist/antagonist class? (select all that apply)

Accepted Answer

Alendronate,ibandronate,risedronate,and zoledronic acid all belong to the bisphosphonate class of drug.Denosumab is a monoclonal antibody.Estrogen/bazedoxifene and raloxifene are from the estrogen agonist/antagonist class of drugs.

Question 7

Which action by a skeletal muscle relaxant is the major mechanism of action?

Accepted Answer

Skeletal muscles require nerve stimulation to contract for voluntary movement.This stimulation starts in the brain.All skeletal muscle relaxants exert their effects by suppressing some activity of nerves in the brain and/or spinal cord (central nervous system)rather than by acting directly on the muscles themselves.Although drowsiness or sleepiness may be induced as a side effect of these drugs,the drowsiness/sleepiness does not cause skeletal muscle relaxation.

Question 8

A patient is prescribed to start cyclobenzaprine (Flexeril).Before administering the drug,you find he has a slow and irregular heartbeat.What is your best action?

Accepted Answer

The most common adverse effects of the cyclobenzaprines are cardiac dysrhythmias and prolonged cardiac conduction.They are not to be used in a patient who has any persistent heart rhythm problem.It is not known whether this patient's slow and irregular heartbeat is persistent.The dose must be held and the prescriber notified.Only the prescriber can substitute a drug from a different class.

Quiz 30: Drug Therapy for Osteoporosis, Arthritis, and Skeletal Muscle Relaxation

For which patient should you question the order for cyclobenzaprine (Flexeril) ?

Which electrolyte imbalance is most likely to trigger skeletal muscle spasms?

A patient who weighs 154 lb is prescribed to receive rasburicase (Elitek)0.2 mg/kg intravenously.The available drug has a concentration of 7.5 mg/mL.How many milliliters should you prepare to administer.

A patient is prescribed to receive methocarbamol 300 mg by direct intravenous push.The drug available is a 10% solution of 1000 mg/10 mL.How many milliliters will you prepare to administer?

A patient taking methocarbamol (Robaxin) for skeletal muscle cramping reports facial flushing.How should you respond?

Which drugs belong to the estrogen agonist/antagonist class? (select all that apply)

Which action by a skeletal muscle relaxant is the major mechanism of action?

A patient is prescribed to start cyclobenzaprine (Flexeril) .Before administering the drug,you find he has a slow and irregular heartbeat.What is your best action?