Question 1

Based on Special Topic 24.1, would taking probiotic health supplements be good for your immunity?

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Question 2

Current medical studies have shown that the T_H1/T_H2 cell ratio can be linked to infertility issues in women suffering recurrent reproductive failure (who have been shown to have higher levels of T_H1). What does a T_H1/T_H2 cell ratio mean, and what part of adaptive immunity is more active in such women?

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Question 3

List the steps for the classical complement cascade. Discuss two ways this cascade results in microbial destruction.

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Question 4

Systemic lupus erythematosus (SLE) is a chronic, inflammatory autoimmune disorder affecting the skin, joints, kidneys, and other organs. A hallmark of lupus is the production of an array of autoantibodies. Some scientists believe that the autoantibody formation seen in lupus is a result of Epstein-Barr virus molecular mimicry. What do these scientists believe has happened in the case of lupus? Give one example as evidential support.

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Question 5

If a person was unable to undergo negative selection during T-cell education, what is T-cell education and why would this be a severe immune problem?

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Question 6

Would treating a person infected with human immunodeficiency virus (HIV) who has recently developed acquired immunodeficiency syndrome (AIDS) using a helper T-cell transfusion work? Why or why not?

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Question 7

X-linked hyper IgM syndrome (XHIM) is an immunodeficiency disorder caused by mutations of the gene encoding CD154. Why is this disease characterized by recurrent infections (starting in childhood) and elevated serum levels of IgM?

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Question 8

Yersinia enterocolitica is an example of a bacterium that can outsmart the adaptive immune system by inhibiting pro-inflammatory cytokine production signal transduction pathways. Give one example of another microbe that can outsmart this system and discuss why this is of benefit from the microbial perspective.

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Question 9

Why are antihistamines good for allergic rhinitis, but NOT for atopic asthma?

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Question 10

A patient presents in the emergency room with large red lesions up and down his arms. His case history reveals that he works for a gardening company, and that this rash most likely developed after clearing a weedy bank two days prior. The resident on duty concludes that the rash is a result of poison ivy exposure. Immunologically speaking, what is going on in this man's body, and what type of immune response is he experiencing?

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Quiz 24: The Adaptive Immune Response