A student asks about the mechanism that results in type II hypersensitivity reactions. What description by the professor is best?
A)Antibodies coat mast cells by binding to receptors that signal its degranulation, followed by a discharge of preformed mediators.
B)Antibodies bind to soluble antigens that were released into body fluids, and the immune complexes are then deposited in the tissues.
C)Cytotoxic T lymphocytes or lymphokine-producing helper T 1 cells directly attack and destroy cellular targets.
D)Antibodies bind to the antigens on the cell surface.

Question

Quizplus · Accepted Answer

The mechanism that results in a type II hypersensitivity reaction begins with antibody binding to tissue-specific antigens or antigens that have attached to particular tissues. The cell can be destroyed by antibody IgG or IgM and activation of the complement cascade through the classical pathway.

A Student Asks About the Mechanism That Results in Type