AST and ALT testing is done to monitor potential liver damage in patients receiving statin drugs.

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Certain drugs can impair liver function and require monitoring of liver enzymes. These drugs include statins and fibrates, pharmaceutical agents used to lower blood cholesterol, and certain antidiabetic and antihypertensive drugs. Liver function must be monitored during therapy with drugs that may cause liver malfunction. Two liver enzymes, aspartate aminotransferase (AST) and alanine aminotransferase (ALT), can be useful for monitoring homeostasis during drug therapy.

AST and ALT Testing Is Done to Monitor Potential Liver