Philadelphia translocation is a specific chromosomal abnormality that occurs from a reciprocal translocation between chromosomes 9 and 22,where parts of these two chromosomes switch places.This abnormality is associated with which disease?
A) Hemophilia A
B) Chronic myelogenous leukemia
C) Obesity
D) Marfan syndrome

Question

Quizplus · Accepted Answer

Philadelphia chromosome or Philadelphia translocation is a specific chromosomal abnormality associated with chronic myelogenous leukemia.It occurs from a reciprocal translocation between chromosomes 9 and 22,where parts of these two chromosomes switch places.Hemophilia A is a sex-linked inheritance.Obesity is being studied with the FTO gene on chromosome 16.Marfan syndrome is classified as a single-gene disorder.

Philadelphia Translocation Is a Specific Chromosomal Abnormality That Occurs from a Reciprocal