The Next Questions Refer to the Following Data on Blood

The next questions refer to the following data on blood types.
$$\begin{array} { l l l l } & \text { Case 1 } & \text { Case 2 } & \text { Case 3 } \\\hline \text { Mother } & \mathrm { A } , \mathrm { Rh } ^ { - } & \mathrm { O } , \mathrm { Rh } ^ { - } & \mathrm { AB } , \mathrm { Rh } ^ { + } \\\text {Fetus } & \mathrm { A } , \mathrm { Rh } ^ { + } & \mathrm { A } , \mathrm { Rh } ^ { - } & \mathrm { A } , \mathrm { Rh } ^ { - }\end{array}$$ Figure 43.2
-In which of the cases could the mother exhibit an anti-Rh-factor reaction to the developing fetus?

A) Case 1 only
B) Case 3 only
C) Cases 1 and 2 only
D) Cases 1, 2, and 3
E) It cannot be determined from the data given.