Use the following information to answer the following questions.
An otherwise healthy student in your class is infected with EBV, the virus that causes infectious mononucleosis. The same student had already been infected when she was a child, and she had merely experienced a mild sore throat and swollen lymph nodes in her neck. This time, though infected, she does not get sick.
-Which of the following is a pathway that would lead to the activation of cytotoxic T cells?
A)B cell contact antigen → helper T cell is activated → clonal selection occurs
B)body cell becomes infected with a virus → new viral proteins appear → class I MHC molecule-antigen complex displayed on cell surface
C)self-tolerance of immune cells → B cells contact antigen → cytokines released
D)complement is secreted → B cell contacts antigen → helper T cell activated → cytokines released
E)cytotoxic T cells → class II MHC molecule-antigen complex displayed → cytokines released → cell lysis

Question

Quizplus · Accepted Answer

Cytotoxic T cells are activated when the body cell becomes infected with a virus and new viral proteins appear. These viral proteins can be displayed on the cell surface in association with class I MHC molecules. This allows for recognition by cytotoxic T cells, which can then attack and kill the infected cell. Pathways A, C, D, and E do not involve activation of cytotoxic T cells.

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