Which of the following statements best describes the termination of transcription in prokaryotes?
A)RNA polymerase transcribes through the polyadenylation signal, causing proteins to associate with the transcript and cut it free from the polymerase.
B)RNA polymerase transcribes through the terminator sequence, causing the polymerase to fall off the DNA and release the transcript.
C)RNA polymerase transcribes through an intron, and the snRNPs cause the polymerase to let go of the transcript.
D)Once transcription has initiated, RNA polymerase transcribes until it reaches the end of the chromosome.
E)RNA polymerase transcribes through a stop codon, causing the polymerase to stop advancing through the gene and release the mRNA.

Question

Quizplus · Accepted Answer

In prokaryotes, termination of transcription occurs when RNA polymerase transcribes through a terminator sequence, which causes the polymerase to fall off the DNA and release the transcript. This terminator sequence typically contains a palindromic sequence followed by a string of adenine residues. Once the polymerase reaches this sequence, it destabilizes the transcription complex and is released from the template DNA. This results in the release of the newly synthesized RNA transcript. Thus, option B is the correct answer.

Which of the Following Statements Best Describes the Termination of Transcription