The following questions refer to this table of codons.

-A peptide has the sequence NH₂-phe-pro-lys-gly-phe-pro-COOH. Which of the following sequences in the coding strand of the DNA could code for this peptide?
A) 3' UUU-CCC-AAA-GGG-UUU-CCC
B) 3' AUG-AAA-GGG-TTT-CCC-AAA-GGG
C) 5' TTT-CCC-AAA-GGG-TTT-CCC
D) 5' GGG-AAA-TTT-AAA-CCC-ACT-GGG
E) 5' ACT-TAC-CAT-AAA-CAT-TAC-UGA

Question

The following questions refer to this table of codons.
 
-A peptide has the sequence NH₂-phe-pro-lys-gly-phe-pro-COOH. Which of the following sequences in the coding strand of the DNA could code for this peptide?
A) 3' UUU-CCC-AAA-GGG-UUU-CCC 
B) 3' AUG-AAA-GGG-TTT-CCC-AAA-GGG 
C) 5' TTT-CCC-AAA-GGG-TTT-CCC 
D) 5' GGG-AAA-TTT-AAA-CCC-ACT-GGG 
E) 5' ACT-TAC-CAT-AAA-CAT-TAC-UGA

Quizplus · Accepted Answer

The correct DNA sequence must match the RNA sequence that codes for the peptide, considering the RNA codons for each amino acid and the fact that DNA is complementary to RNA. The peptide sequence is NH₂-phe-pro-lys-gly-phe-pro-COOH, which corresponds to the RNA codons UUU (phe), CCC (pro), AAA (lys), GGG (gly), UUU (phe), CCC (pro). The DNA sequence that is complementary to this RNA sequence is 5' TTT-CCC-AAA-GGG-TTT-CCC, which matches option C.

The Following Questions Refer to This Table of Codons