The difference between uncompetitive and noncompetitive inhibitors is that
A)uncompetitive inhibitors bind irreversibly.
B)1 / V max is the same for all concentrations of uncompetitive inhibitors.
C)an uncompetitive inhibitor binds only to ES.
D)a competitive inhibitor binds only to E.

Question

Quizplus · Accepted Answer

Uncompetitive inhibitors bind only to the ES complex, not the free enzyme or substrate. This is what distinguishes them from noncompetitive inhibitors, which can bind to either the enzyme or the enzyme-substrate complex. The other answer choices are either incorrect (A) or not directly relevant to the difference between uncompetitive and noncompetitive inhibitors (B and D).

The Difference Between Uncompetitive and Noncompetitive Inhibitors Is That