Which of the following best describes the role of proteins that contain a basic helix-loop-helix (bHLH) domain, such as in the MyoD protein involved in the determination of muscle lineages?
A) binds to specific regions of DNA
B) interacts with the splicesome
C) participates in the polyadenylation of mRNAs
D) participates in the splicing of mRNAs
E) promotes the transnuclear transport of processed mRNAs

Question

Quizplus · Accepted Answer

Proteins with a basic helix-loop-helix (bHLH) domain, like MyoD, are transcription factors that bind to specific DNA sequences to regulate gene expression. The helix-loop-helix domain is a protein interaction domain characteristic of numerous transcription factors. The basic region is required for the recognition of, and binding to, specific DNA sequences.

Which of the Following Best Describes the Role of Proteins