Which of the following relates to allosteric enzymes?
A) they are inactive on their substrates in the absence of accessory proteins
B) they can bind more than one substrate simultaneously
C) they can convert multiple different substrates to product
D) they possess binding sites for regulatory molecules in addition to substrate-binding sites
E) they require additional cofactor-binding sites for subsequent binding of substrate

Question

Quizplus · Accepted Answer

Allosteric enzymes have regulatory sites where molecules can bind and influence the enzyme's activity, separate from the active site where substrates bind.  Allosteric enzymes are enzymes that change their conformational orientations upon binding of an effector which results in an apparent change in binding affinity at a different ligand-binding site. This action at a distance through binding of one ligand (or allosteric effector) affecting the binding of another at a distinctly different site is the essence of the allosteric concept.

Which of the Following Relates to Allosteric Enzymes