The standard free-energy change (DG0′) for the hydrolysis of phosphoenolpyruvate (PEP) is −14.8 kcal/mol.' The DG0' for the hydrolysis of
ATP is −7.3 kcal/mol. What is the ΔG^0' for the following reaction? Phosphoenolpyruvate + ADP → pyruvate + ATP

Question

Quizplus · Accepted Answer

The reaction involves the hydrolysis of PEP and the synthesis of ATP. The ΔG^0' for the reaction is the difference between the ΔG^0' of PEP hydrolysis and ATP synthesis: -14.8 kcal/mol + 7.3 kcal/mol = -7.5 kcal/mol.

The Standard Free-Energy Change (DG0′) for the Hydrolysis of Phosphoenolpyruvate