Small interfering RNAs and microRNAs are tiny RNAs produced when larger double-stranded RNA molecules are cleaved by the enzyme Dicer. Small interfering RNAs and microRNAs participate in a variety of processes, including mRNA degradation, the inhibition of translation, the methylation of DNA, and chromatin remodeling. Piwi-interacting RNAs are found in the germ cells of animals and inhibit transposons.
-How do siRNAs and miRNAs target specific mRNAs for degradation or for the repression of translation?
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