Which of the following statements about the function of the Dicer RNA endonuclease complex is INCORRECT?
A) It processes pre-miRNA.
B) It processes introduced double stranded RNA.
C) It processes pre-miRNA and introduced double stranded RNA.
D) It creates double stranded RNAs 25-30 nucleotides in length.
E) It creates siRNAs that do not bind with the RISC complex.

Question

Quizplus · Accepted Answer

Dicer is involved in the processing of pre-miRNA and double-stranded RNA into small RNA fragments, such as siRNAs and miRNAs, which do bind with the RISC complex to mediate gene silencing. Therefore, the statement that it creates siRNAs that do not bind with the RISC complex is incorrect.

Which of the Following Statements About the Function of the Dicer