Question 1

A patient arrives and asks you to re-fill his Ambien prescription. There are no refills left. Which is the best approach for you to take?

Accepted Answer

Ambien is generally given for 7-10 days. The patient's doctor is the only one who can order a refill.

Question 2

Dimenhydrinate is used as an________?

Accepted Answer

Dimenhydrinate (Dramamine) is an anticholinergic used to treat nausea, vomiting, and vertigo.

Question 3

Which of the following are possible signs/symptoms/complications of lansoprazole?
I. GI hemorrhage
II. Cerebrovascular accident
III. Asthma
IV. Myocardial infarction

Accepted Answer

All the complications listed are possible with lansoprazole use.

Question 4

What do IND and NDA stand for respectively?

Accepted Answer

IND and NDA are acronyms for "Investigation New Drug and "New Drug Application" respectively.

Question 5

Tizanidine is a(n) _______ used to treat ______ and which rarely has the adverse effect of inducing _______.

Accepted Answer

Tizanidine is a centrally-acting alpha-adrenergic agonist used to treat increased muscle tone (spasticity) and occasionally results in unexpected hypotension. It is marketed as Zanaflex.

Question 6

Which of the following forms is erythromycin available in?
I. Oral suspension; 200 mg/5 mL and 400mg/5 mL
II. Powder for injection; 500 mg, 1 g
III. Tablet; 200, 250, 333, 400 and 500 mg
IV. Capsule; 250 mg
V. Topical ointment; 2%

Accepted Answer

Erythromycin, a macrolide antibiotic, is available in all the forms and dosages listed.

Question 7

What is the mechanism of action of gentamicin?

Accepted Answer

Gentamicin is an aminoglycoside and is bacteriocidal against Gram (-) bacteria by irreversibly binding the 30S subunit of bacterial ribosomes and NOT the 50S subunit. The mechanism of action described for 4th generation cephalosporins and monobactams is correct.

Question 8

Which of the following is likely to be true of a Phase I clinical trial?

Accepted Answer

Phase I clinical trials are most often done with small groups of patients with a variety of diseases or cancers-the main thrust of a Phase I clinical trial is to determine the safe dose range of an agent and if there is a rationale to continue testing and main side effects. Phase I clinical trials are not retrospective (historic) in nature.

Question 9

Which of the following conditions would call for the use of flumazenil?
I. Benzodiazepine overdose
II. H1N1 infection
III. Community acquired viral pneumonia

Accepted Answer

Flumazenil is an antidote for benzodiazepine overdose.

Question 10

Which of the following forms is drotrecogin alfa available in?
I. Oral suspension; 200 mg/5 mL and 400mg/5 mL
II. Lyophilized powder for injection; 5 and 20 mg
III. Tablet; 200, 250, and 500 mg
IV. Capsule; 250 and 500 mg

Accepted Answer

Drotrecogin alfa is an activated recombinant Protein C used in the treatment of severe sepsis. It is only available as a lyophilized powder for injection at 5 and 20 mg.

Question 11

Which of the following are potential agents used in the treatment of refractory Crohn's disease?

Accepted Answer

Azothiaprine and methotrexate are immunosuppressants used in the treatment of Crohn's disease. Filgrastm (Neupogen) is a granulocyte stimulating factor used after myelosuppressive therapy. Mercaptopurine is an antineoplastic used to treat acute leukemias and Levonorgestrel is a contraceptive in Plan B and in the IUD Mirena.

Question 12

What is Xifaxan used to treat?

Accepted Answer

Xifaxan is the trade name for rifaxamin, a rifampin-like antibiotic used to treat diarrhea caused by non-invasive strains of E. coli.

Question 13

Metronidazole is known to have a disulfiram-like reaction with alcohol. Which would be the most appropriate form for dosing metronidazole?

Accepted Answer

All the forms listed except a suspension use alcohol as the solvent. Since a disulfiram reaction is likely, only the non-alcohol method of delivery is appropriate.

Question 14

Which of the following drugs is a combination product?
I. Maxzide
II. Vytorin
III. Lomotil

Accepted Answer

Maxzide is a combination of hydrochlorothiazide and triamterene and is an anti-hypertensive. Vytorin is a combination of ezetimibe and simvastatin and is an anti-hyperlipidemic combination. Lomotil is a combination of atropine and diphenoxylate and is an antidiarrheal.

Question 15

For the following chemotherapeutic agents, determine the incorrect combination of agent / pharmacologic class.
I. Tacrine / acetylcholine agonist
II. Atomoxetine / SSRI
III. Quetiapine / dibenzothiazepine
IV. Clindamycin / macrolide

Accepted Answer

Tacrine is a cholinesterase inhibitor and Clindamycin is a lincosamide. In choices II and III, the drugs are correctly paired with the pharmacologic class.

Quiz 1: Pharmacy Technician Certification

A patient arrives and asks you to re-fill his Ambien prescription. There are no refills left. Which is the best approach for you to take?

Dimenhydrinate is used as an________?

Which of the following are possible signs/symptoms/complications of lansoprazole? I. GI hemorrhage II. Cerebrovascular accident III. Asthma IV. Myocardial infarction

What do IND and NDA stand for respectively?

Tizanidine is a(n) _ used to treat and which rarely has the adverse effect of inducing ___.

Which of the following forms is erythromycin available in? I. Oral suspension; 200 mg/5 mL and 400mg/5 mL II. Powder for injection; 500 mg, 1 g III. Tablet; 200, 250, 333, 400 and 500 mg IV. Capsule; 250 mg V. Topical ointment; 2%

What is the mechanism of action of gentamicin?

Which of the following is likely to be true of a Phase I clinical trial?

Which of the following conditions would call for the use of flumazenil? I. Benzodiazepine overdose II. H1N1 infection III. Community acquired viral pneumonia

Which of the following forms is drotrecogin alfa available in? I. Oral suspension; 200 mg/5 mL and 400mg/5 mL II. Lyophilized powder for injection; 5 and 20 mg III. Tablet; 200, 250, and 500 mg IV. Capsule; 250 and 500 mg

Which of the following are potential agents used in the treatment of refractory Crohn's disease?

What is Xifaxan used to treat?

Metronidazole is known to have a disulfiram-like reaction with alcohol. Which would be the most appropriate form for dosing metronidazole?

Which of the following drugs is a combination product? I. Maxzide II. Vytorin III. Lomotil

For the following chemotherapeutic agents, determine the incorrect combination of agent / pharmacologic class. I. Tacrine / acetylcholine agonist II. Atomoxetine / SSRI III. Quetiapine / dibenzothiazepine IV. Clindamycin / macrolide