Question 1

The nurse is caring for a client who has been prescribed a fluoroquinolone for the treatment of a respiratory infection. The nurse is explaining to the client that this class of medications affects DNA replication by inhibiting the ________ strands of DNA from migrating to the opposite sides of the cell, therefore inhibiting division.
Record your answer rounding to the nearest whole number.

Accepted Answer

The fluoroquinolone antibiotics act on two enzymes in the DNA replication process. First, they bind to DNA gyrase, inhibiting its ability to relax the supercoiling of the bacterial DNA. When the replication enzymes reach an area still in a supercoiled state, replication terminates. A second mechanism is binding to topoisomerase IV. When this occurs, the two daughter DNA strands cannot migrate to opposite sides of the cell, and division cannot be completed.

Question 2

The nurse is caring for a female client with an uncomplicated UTI that is being treated with ciprofloxacin hydrochloride (Proquin XR). The client asks the nurse how long she will need to take this medication. The nurse tells the client she will have to take the medication for ________ days.
Record your answer rounding to the nearest whole number.

Accepted Answer

Approved in 2005, ciprofloxacin hydrochloride (Proquin XR) contains only the hydrochloride salt and has been formulated to cause less nausea, vomiting, and diarrhea than other formulations. ciprofloxacin hydrochloride (Proquin XR) is administered for only 3 days and is only approved for uncomplicated UTI (acute cystitis).

Question 3

The nurse is administering ciprofloxacin to a client with acute cystitis. The nurse anticipates administering this drug to the client twice a day because the duration of action is ________ hours.
Record your answer rounding to the nearest whole number.

Accepted Answer

The duration of action for ciprofloxacin is 12 hours; therefore, the nurse anticipates the need to administer the medication twice a day.

Question 4

The nurse is preparing to discharge a client with a urinary tract infection (UTI) from the urgent care center. The nurse tells the client to call the healthcare provider is the current fever does not diminish below ________ degrees Celsius within 3 days.
Record your answer rounding to one decimal place.

Accepted Answer

Teach the client to report a fever that does not diminish below 37.8°C (100°F) or per the parameters set by the healthcare provider within 3 days, increasing signs and symptoms of infection, or symptoms that remain after taking the entire course of the antibacterial drug.

Question 5

How many generations of cephalosporins exert their antibacterial effect by interfering with the synthesis of the bacterial cell wall?
A) 5
B) 4
C) 3
D) 2

Accepted Answer

There are five generations of cephalosporins that interfere with the synthesis of bacterial cell wall.

Question 6

What primary material in the bacterial cell wall forms the peptidoglycan?
A) Carbohydrate and protein chains
B) Fat and glycogen layers
C) Single, layered lipids and ribosomes
D) Sodium and potassium cells

Accepted Answer

The bacterial cell wall is composed of carbohydrates and protein.

Question 7

The nurse has received an order to give imipenem-cilastatin (Primaxin) to a client. Prior to the administration of this medication, the nurse should assess which of the following?
A) Patency of the IV line
B) Vital signs
C) The client's allergies
D) Laboratory values

Accepted Answer

Imipenem-cilastatin (Primaxin) must be given parentally. The patency of the IV line must be ensured prior to administration.

Question 8

The nurse explains to a nursing student that drugs that activate the parasympathetic branch of the autonomic nervous system:
A) relax bronchiolar smooth muscle.
B) result in airway diameter narrowing.
C) decrease labored breathing
D) increase production of viscous secretions.

Accepted Answer

Drugs that activate the parasympathetic branch of the autonomic nervous system cause bronchiolar smooth muscle to contract, the airway diameter to narrow, and bronchoconstriction to occur.

Quiz 12: Antibiotics and Autonomic Nervous System Activation

The nurse is administering ciprofloxacin to a client with acute cystitis. The nurse anticipates administering this drug to the client twice a day because the duration of action is ________ hours. Record your answer rounding to the nearest whole number.

How many generations of cephalosporins exert their antibacterial effect by interfering with the synthesis of the bacterial cell wall? A) 5 B) 4 C) 3 D) 2

What primary material in the bacterial cell wall forms the peptidoglycan? A) Carbohydrate and protein chains B) Fat and glycogen layers C) Single, layered lipids and ribosomes D) Sodium and potassium cells

The nurse has received an order to give imipenem-cilastatin (Primaxin) to a client. Prior to the administration of this medication, the nurse should assess which of the following? A) Patency of the IV line B) Vital signs C) The client's allergies D) Laboratory values

The nurse explains to a nursing student that drugs that activate the parasympathetic branch of the autonomic nervous system: A) relax bronchiolar smooth muscle. B) result in airway diameter narrowing. C) decrease labored breathing D) increase production of viscous secretions.