Which symptom would not be expected in an animal treated bilaterally with 6-OHDA?
A) Decreased interest in motivated behaviors such as eating and drinking
B) Difficulty initiating movement
C) Increased locomotor activity
D) Sensory neglect

Question

Quizplus · Accepted Answer

Bilateral treatment with 6-OHDA is commonly used to induce a Parkinson's disease-like state in animals, characterized by motor symptoms such as difficulty initiating movement (akin to bradykinesia in humans) and sensory neglect. Other symptoms may include decreased interest in motivated behaviors such as eating and drinking, which are indicative of anhedonia, and abnormal posture or gait. However, increased locomotor activity would be an unexpected symptom in this context, as it suggests hyperactivity or agitation rather than the typical hypokinetic state associated with Parkinson's disease.

Which Symptom Would Not Be Expected in an Animal Treated