Which of the following deletions will not change the reading frame of a gene?
A) One nucleotide
B) Two nucleotides
C) Three nucleotides
D) Four nucleotides

Question

Quizplus · Accepted Answer

A deletion of three nucleotides will only remove one codon (which consists of three nucleotides) from the gene sequence, but will not shift the reading frame. This is because the deletion will still maintain the triplet nucleotide code used to translate genetic information into proteins. A deletion of one or two nucleotides will cause a frameshift mutation, where the reading frame will shift by one or two nucleotides, resulting in a completely different amino acid sequence. A deletion of four nucleotides will cause the deletion of two codons, which will result in a frameshift mutation and a different amino acid sequence.

Which of the Following Deletions Will Not Change the Reading