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Actin Filaments Are a Major Element of the Cytoskeleton

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Actin filaments are a major element of the cytoskeleton. The cytoskeleton provides a framework for the cell and acts as a scaffold that both determines cell shape and positions organelles within cells. For example, the cytoskeleton provides the tracks along which organelles move. At the same time, the cytoskeleton is subject to cleavage by proteins like cofilin. What is the apparent function of cofilin in creating a dynamic cytoskeleton?

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Cofilin is an actin-binding protein, and...

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