The importance of leptin is indicated by the fact that:
A)Injecting leptin into ob/ob mice reduced their weight.
B)Injecting leptin into db/db mice increased their weight.
C)Injecting leptin into ob/ob mice increased their weight.
D)Injecting leptin into db/db mice decresed their weight.

Question

Quizplus · Accepted Answer

Leptin is a hormone produced by adipose tissue that helps regulate body weight and appetite by inhibiting hunger. Ob/ob mice lack the ability to produce leptin and exhibit extreme obesity. Injecting leptin into ob/ob mice reduces their weight by reducing their appetite and increasing their energy expenditure. On the other hand, db/db mice have a mutation in the leptin receptor and are resistant to the effects of leptin. Injecting leptin into db/db mice does not decrease their weight and may even increase it by promoting leptin resistance. Therefore, choice A is the best choice because it correctly indicates the positive effect of leptin on weight loss in ob/ob mice.

The Importance of Leptin Is Indicated by the Fact That