As they relate to randomized controlled trials, which one of the following levels of evidence matches with its hierarchical level? (Note: Level 1 is the highest level of evidence and Level 5 is the lowest level of evidence)
A) Level 5: Strong evidence from at least one systematic review of multiple well-designed randomized controlled trials
B) Level 3: Strong evidence from at least one or more properly designed randomized controlled trials of appropriate size
C) Level 2: Evidence from well-designed trials without randomization, single group pre-post, cohort, time series, or matched case-controlled studies
D) Level 4: Evidence from well-designed nonexperimental studies from more than one center or research group
E) Level 1: Opinions of respected authorities, based on clinical evidence, descriptive studies, or reports of expert committees
Correct Answer:
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