In lamellipodia, actin polymerization is nucleated by ...(1), while depolymerization is catalyzed by ...(2).
A) (1) formin; (2) gelsolin
B) (1) Arp 2/3 complex; (2) gelsolin
C) (1) formin; (2) cofilin
D) (1) Arp 2/3 complex; (2) cofilin
E) (1) formin; (2) capping protein

Question

Quizplus · Accepted Answer

The Arp 2/3 complex nucleates a two-dimensional web of actin filaments in a lamellipodium. Behind the leading edge, cofilin disassembles older filaments which contain ADP-actin.

In Lamellipodia, Actin Polymerization Is Nucleated by