How is membrane protrusion by blebbing different from that by lamellipodia?
A) Blebbing usually occurs on a rigid substratum such as glass, whereas lamellipodia form on pliable substrata.
B) Blebbing is mostly observed in vitro, whereas lamellipodia are observed both in vitro and in vivo.
C) Blebbing does not involve myosin II activity, but formation of lamellipodia does.
D) Blebbing requires loss of membrane interaction with actin filaments, whereas lamellipodia require a close interaction between the two.
E) All of the above.

Question

Quizplus · Accepted Answer

Blebbing is mostly observed in vivo where the substratum is pliable. Both lamellipodia formation and blebbing require the activity of myosin II at some point. One of the key differences between the two is in their requirements for membrane interaction with cortical actin filaments.

How Is Membrane Protrusion by Blebbing Different from That by Lamellipodia