The following graph shows the change in the concentration of a protein (A) over time as a fraction of the final steady-state level. The two curves (1 and 2) in the graph are simulations with similar parameters except that one of them involves a negative feedback loop in which A activates the expression of a repressor protein which in turn represses the expression of A. Which curve (1 or 2) corresponds to the simulation with the negative feedback loop? Write down 1 or 2 as your answer.

Question

Quizplus · Accepted Answer

Negative feedback can cause oscillations and, as seen in this example, overshoots in approaching the steady state. This allows the system to reach steady state faster. Please refer to Figure 8-76.

The Following Graph Shows the Change in the Concentration of a Protein