Question 1

Ranula is the clinical designation of a salivary gland lesion that occurs in which of the following locations?

Accepted Answer

Ranula is a type of mucous retention cyst that specifically occurs in the floor of the mouth, often associated with the sublingual glands.

Question 2

All the following may develop in minor salivary gland tissue. However, one is rarely seen in major glands. It is:

Accepted Answer

Polymorphous low-grade adenocarcinoma primarily occurs in the minor salivary glands, particularly in the palate, and is rarely seen in the major salivary glands.

Question 3

The circumscribed salivary gland tumor that is composed of a benign mixture of neoplastic ductal epithelium and myoepithelium-derived connective tissue is known as:

Accepted Answer

Pleomorphic adenoma, also known as a mixed tumor, is characterized by a benign mixture of neoplastic ductal epithelium and myoepithelium-derived connective tissue, making it the correct answer.

Question 4

The management of maxillary sinus retention cysts that are typically discovered during routine panoramic radiographic examinations is:

Accepted Answer

Maxillary sinus retention cysts are usually asymptomatic and discovered incidentally during routine radiographic examinations. The standard management approach for these cysts is observation, as they often do not cause symptoms or require intervention.

Question 5

Sialoliths are associated with which of the following?

Accepted Answer

Sialoliths, or salivary stones, can cause pain, duct obstruction, secondary gland infection, and mucous retention, as they block the flow of saliva, leading to these complications.

Question 6

On routine panographic examination, a uniform round opacity measuring 1.5 cm in diameter was noted in the floor of the maxillary sinus of a 24-year-old man. All normal landmarks in the maxilla appeared intact. The patient had no symptoms and no history of sinus problems. This lesion most likely represents which of the following?

Accepted Answer

A maxillary sinus retention cyst is a common, asymptomatic finding on radiographs, often discovered incidentally during routine examinations. It is characterized by a round or dome-shaped radiopacity in the sinus, not typically associated with symptoms or significant history, fitting the description provided.

Question 7

Which of the following is the most likely clinical presentation of mixed tumor of minor salivary gland?

Accepted Answer

Mixed tumors of the minor salivary glands, also known as pleomorphic adenomas, typically present as firm, painless, submucosal masses. They are most commonly found in the palate area but can occur in other locations where minor salivary glands are present.

Question 8

A labial salivary gland biopsy showed the replacement of normal parenchyma with granulomas. There was no scarring and no ductal dilatation. This biopsy suggests:

Accepted Answer

The presence of granulomas replacing normal parenchyma in a labial salivary gland biopsy, without scarring or ductal dilatation, is indicative of sarcoidosis. Sarcoidosis is characterized by the formation of non-caseating granulomas in various organs, including the salivary glands.

Question 9

Necrotizing sialometaplasia:

Accepted Answer

Necrotizing sialometaplasia is a benign condition that can occur in the palate and may mimic carcinoma both clinically and microscopically due to its presentation and histological features. It is related to ischemic necrosis of the salivary glands.

Question 10

Trauma is the cause of which of the following?

Accepted Answer

The mucous extravasation phenomenon, also known as a mucocele, is a common lesion in the oral cavity resulting from the rupture of a salivary gland duct and the spillage of mucin into the surrounding tissues. This can often be caused by local trauma, such as biting the inner lip or cheek.

Question 11

A biopsy of a nodular lesion of the tongue showed several noncaseating granulomas. The patient was found to have similar lesions in the hilar regions of his lungs. He most likely has which of the following?

Accepted Answer

Sarcoidosis is characterized by the presence of noncaseating granulomas in multiple organs, including the lungs and sometimes the tongue, which matches the description given.

Question 12

Which of the following is a common cause of xerostomia in the elderly?

Accepted Answer

Systemic drugs are a common cause of xerostomia (dry mouth) in the elderly, as many medications can reduce saliva production as a side effect.

Question 13

An adult patient complained of a 1 * 1 cm slightly tender nonulcerated mass in his lower lip. The patient believes that the lesion developed after he bit his lip several weeks ago. This would most likely be which of the following?

Accepted Answer

A mucocele is a common lesion that occurs due to the rupture of a salivary gland duct, often following trauma such as lip biting, leading to the accumulation of mucus in the surrounding tissue.

Question 14

Patients with Sjögren's syndrome have increased risk for developing which of the following?

Accepted Answer

Patients with Sjögren's syndrome have an increased risk of developing lymphoma, particularly non-Hodgkin lymphoma, as part of their autoimmune disorder.

Question 15

Basal cell adenoma:

Accepted Answer

The answer of Basal cell adenoma:
...

Question 16

Sialolithiasis is a phenomenon that most likely would be associated with which of the following glands?

Accepted Answer

Sialolithiasis most commonly affects the submandibular glands due to the higher mucin content of their saliva and the upward flow of saliva against gravity, which can lead to the formation of salivary stones.

Question 17

Mixed tumor of salivary glands:

Accepted Answer

Mixed tumors of salivary glands, also known as pleomorphic adenomas, are characterized by containing both epithelial and connective tissue components, which can sometimes resemble cartilage. They are not specifically caused by smoking, and while they can eventually become malignant, they do not frequently metastasize to local lymph nodes in their benign form.

Question 18

Which of the following disorders places the patient at risk for the appearance or development of a malignancy?

Accepted Answer

All the options listed are associated with an increased risk of developing malignancies. Primary Sjögren's syndrome is linked to a higher risk of lymphoma; proliferative verrucous leukoplakia is a high-risk oral precancerous condition; neurofibromatosis, particularly type 1, is associated with various types of tumors, including malignant peripheral nerve sheath tumors; and MEN III, also known as Multiple Endocrine Neoplasia type 2B, is associated with medullary thyroid carcinoma and pheochromocytoma, among other tumors.

Quiz 8: Salivary Gland Diseases