Hematology Clinical Principles

Medicine

Quiz 33 :
Myeloproliferative Neoplasms

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Quiz 33 :
Myeloproliferative Neoplasms

A Acute myeloid leukemia is not included in the chronic myeloproliferative disorders.All the other conditions listed are part of this classification.

C The chronic myeloproliferative disorders all have increased blood cells,although which one (or ones)varies depending on the condition.They also all have overlapping clinical features.The Philadelphia chromosome is found only in chronic myelogenous leukemia within this classification.Polycythemia vera uniquely has an increased red cell mass,and serious thromboembolic complications are primarily seen in essential thrombocythemia,although they also can be a complication of polycythemia vera when the patient is treated with phlebotomy only.

B Myeloblasts plus promyelocytes are usually present between 1% and 5% in chronic myelogenous leukemia.A total of 20% blasts plus promyelocytes is proposed for the classification of chronic myelogenous leukemia accelerated phase.All the other findings listed are characteristic of chronic myelogenous leukemia.