Lactate is formed and accumulates when the rate of glycolytic production of pyruvate and NADH exceeds the rate at which these products are shuttled into the mitochondria.

Question

Quizplus · Accepted Answer

This statement is true. Lactate is formed and accumulates when there is an excess of pyruvate and NADH produced by glycolysis that cannot be shuttled into the mitochondria for further metabolism through oxidative phosphorylation. This can occur in conditions such as intense exercise or oxygen deprivation, leading to the buildup of lactate in the bloodstream.

Lactate Is Formed and Accumulates When the Rate of Glycolytic