What is the function of the 5'-3' exonuclease activity of DNA polymerase I?
A)It removes mismatched nucleotides that have been incorporated by mistake.
B)It replaces mismatched nucleotides with the correctly matched nucleotides.
C)It removes the DNA primer laid down by the primase at the 5' end of the Okazaki fragment.
D)It removes the RNA primer laid down by the primase at the 5' end of the Okazaki fragment.
E)It nicks DNA to create a primer in the middle of a DNA chain.

Question

What is the function of the 5'->3' exonuclease activity of DNA polymerase I?
A)It removes mismatched nucleotides that have been incorporated by mistake.
B)It replaces mismatched nucleotides with the correctly matched nucleotides.
C)It removes the DNA primer laid down by the primase at the 5' end of the Okazaki fragment.
D)It removes the RNA primer laid down by the primase at the 5' end of the Okazaki fragment.
E)It nicks DNA to create a primer in the middle of a DNA chain.

Quizplus · Accepted Answer

The 5'->3' exonuclease activity of DNA polymerase I removes the RNA primer laid down by the primase at the 5' end of the Okazaki fragment, allowing DNA polymerase I to replace it with DNA nucleotides. This process is known as primer removal or primer excision.

What Is the Function of the 5'->3' Exonuclease Activity of DNA