Which of the following is the correct Hill function for activation? A) Y = β(X*)^-1/Kⁿ(X*)ⁿ B) Y = β(X*)ⁿ/(Kⁿ + (X*)ⁿ) C) Y = β(X*)ⁿ/Kⁿ D) Y = β(X*)/Kⁿ E) Y = β(X*)ⁿ/K(X*)ⁿ

Question

Quizplus · Accepted Answer

The Hill function for activation is typically given by: Y = β[X^n / (K^n + X^n)] where Y is the response, X is the concentration of the activator, β is the maximum response, K is the concentration of the activator required to reach half-maximal response, and n is the Hill coefficient, which determines the steepness of the response curve. Option B is the only one that matches this form, with the variables rewritten as: Y = β(X*)ⁿ / [Kⁿ + (X*)ⁿ] Here, (X*) represents the concentration of the activator, ^and represent different protein states, and n is the Hill coefficient. Therefore, option B is the best choice.

Which of the Following Is the Correct Hill Function for Activation