Assume That a Series of Compounds Has Been Discovered in Neurospora.Compounds

Assume that a series of compounds has been discovered in Neurospora.Compounds A-F appear to be members of an enzyme pathway.Several mutations have been identified and strains 1-4 each contain a single mutation.Shown below are five possible pathways.Choose the pathway that best fits the data presented.[Growth in minimal media with supplements is shown by (+) ,no growth is shown by (o) .] $\begin{array}{|l|l|l|l|l|l|l|}\hline \text { Strain } & \mathrm{A} & \mathrm{B} & \mathrm{C} & \mathrm{D} & \mathrm{E} & \mathrm{F} \\\hline 1 & 0 & 0 & 0 & + & 0 & \mathrm{o} \\\hline 2 & 0 & 0 & 0 & 0 & 0 & + \\\hline 3 & 0 & 0 & 0 & 0 & + & + \\\hline 4 & 0 & 0 & + & 0 & 0 & \circ \\\hline\end{array}$

A) A ? B ? C ? D ? E ? F
B) A ? B ? C ? F ? E ? D
C)
$$\begin{array} { l } \mathrm { A } \rightarrow \mathrm { B } \rightarrow \mathrm { C } \rightarrow \mathrm { D } \\\downarrow \\\mathrm { E } \rightarrow \mathrm { F }\end{array}$$
D)
$$\begin{aligned}\mathrm { A } \rightarrow & \mathrm { B } \rightarrow \mathrm { C } \rightarrow \mathrm { D } \\& \downarrow \\& \mathrm { E } \rightarrow \mathrm { F }\end{aligned}$$
E)
$$\begin{aligned}\mathrm { A } \rightarrow \mathrm { B } \rightarrow & \mathrm { C } \rightarrow \mathrm { D } \\& \downarrow \\& \mathrm { E } \rightarrow \mathrm { F }\end{aligned}$$