Which One of the Following Occurs with Each Cycle of the Sodium-Potassium

Which one of the following occurs with each cycle of the sodium-potassium pump?

A) Sodium is moved into the cell, creating a net negative charge outside the cell.
B) The net effect is removal of one osmotic particle and one positive charge from inside the cell.
C) The net effect is removal of one osmotic particle and one negative charge from inside the cell.
D) The inside of the cell becomes more negative as potassium is pumped out.
E) Two potassium ions and three sodium ions are pumped out of the cell.