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Fundamentals of Molecular Virology Study Set 1

Biology

Quiz 12 :

Flaviviruses

Quiz 12 :

Flaviviruses

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Which of the following diseases is caused by a member of the flavivirus family?
Free
Multiple Choice
Answer:

Answer:

E

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A cloned DNA copy of the yellow fever virus can be used to produce infectious viral RNA.
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True False
Answer:

Answer:

True

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The yellow fever vaccine strain has 32 amino acid mutations in comparison to the wildtype pathogenic virus strain.Which of the following genes contains the majority of these amino acid substitutions?
Free
Multiple Choice
Answer:

Answer:

C

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Infection with a second strain of Dengue fever virus within two years of having had the first strain causes Dengue Hemorrhagic Fever.
True False
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Which of the following describes the phenomenon of antibody-dependent enhancement?
Multiple Choice
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When is the "pr" region cleaved by the protease furin from the prM protein of flaviviruses?
Multiple Choice
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Which of the following cellular proteases helps to process the polyprotein of flaviviruses?
Multiple Choice
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In the mature flavivirus virion,the fusion peptide on the E protein is buried in the dimer interface.Which of the following conditions causes the fusion peptide to become exposed?
Multiple Choice
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Which of the following techniques was used to isolate the flavivirus Hepatitis C virus?
Multiple Choice
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The hydrophobic region of the flavivirus capsid protein is thought to do which of the following?
Multiple Choice
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Which of the following proteins from flaviviruses has the RNA-dependent RNA polymerase activity?
Multiple Choice
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Which of the following conditions is required to induce fusion of the flavivirus envelope with the host cell membrane?
Multiple Choice
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The nonstructural proteins of flaviviruses are produced on the rough ER and have membrane spanning domains.Which of the following explains why the nonstructural proteins are localized to cellular membranes?
Multiple Choice
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West Nile Virus was introduced into the United States in 1999 and became an endemic infection over the next several years.Which of the following wild animal populations does this virus circulate in?
Multiple Choice
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Flavivirus virions obtain their envelopes from the cellular membranes of which of the following organelles?
Multiple Choice
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Which of the following describes the primary mechanism of transmission of the flavivirus Hepatitis C?
Multiple Choice
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How was Yellow Fever Virus introduced into the New World from Africa?
Multiple Choice
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Which of the following describes the reason why the precursor to the capsid protein from flaviviruses has a membrane spanning domain?
Multiple Choice
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Which of the following statements comparing flaviviruses with picornaviruses is FALSE?
Multiple Choice
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Which of the following statements comparing flaviviruses with togaviruses is FALSE?
Multiple Choice
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