Regulatory transcription factors
A) influence the assembly of the basal transcription complex.
B) open the two strands of DNA, so RNA polymerase can begin transcription.
C) influence the binding of sigma factor to DNA.
D) influence the degree of unwinding of DNA at the promoter.

Question

Quizplus · Accepted Answer

Regulatory transcription factors do not directly open the two strands of DNA or influence the binding of sigma factor to DNA. Rather, they influence the assembly of the basal transcription complex, which includes RNA polymerase and other proteins necessary for transcription. The degree of unwinding of DNA at the promoter is also influenced by other factors, such as nucleosome positioning and chromatin remodeling enzymes.

Regulatory Transcription Factors