Twenty- five years ago, when Oshima and colleagues discovered that a mutation in the GAL4 gene led to the inability to synthesize all five enzymes required for galactose catabolism breakdown), they couldn't be blamed for wanting to apply a bacterial model to explain this finding. What they expected, but did not find, was
A) for chromatin decondensation to play an important role in regulating the genes of galactose catabolism.
B) for all five genes to constitute an operon.
C) five widely separated genes, each containing a GAL4 binding site in its regulatory region.
D) for transcription to be important in regulating the genes of galactose catabolism.

Question

Quizplus · Accepted Answer

The researchers expected all five genes involved in galactose catabolism to be in the same operon, but this was not the case. Instead, the genes were found to be scattered throughout the genome, with each one having its own regulatory region containing a binding site for the GAL4 protein.

Twenty- Five Years Ago, When Oshima and Colleagues Discovered That