Question 1

The client has been ordered treatment with Gantanol. The highest priority instruction to provide this client is:

Accepted Answer

The client who is being treated with Gantanol should increase his or her fluid intake to at least 2 L daily.

Question 2

A client is ordered to receive co-trimoxazole (Bactrim, Septra). The nurse assesses for side effects. What causes the nurse the greatest concern?

Accepted Answer

Although all of these may be side effects of this medication, neutropenia and agranulocytosis causes most concern because of immunosuppression and the potential for infections.

Question 3

A nurse is aware that crystalluria is a common problem with sulfonamides. What is a nursing intervention to prevent this problem?

Accepted Answer

Crystalluria and kidney stones may occur related to these medications. A brisk urine flow decreases sedimentation. There is no need for this medication to be IV.

Question 4

Co-trimoxazole (Bactrim, Septra) has a half-life of 8 to 12 hours. Based on this information, the nurse decides to administer the drug at which time(s) each day?

Accepted Answer

Sulfonamides, like co-trimoxazole, are scheduled bid.

Question 5

A client with type 2 diabetes is treated with a sulfonylurea agent. The client is diagnosed with a urinary tract infection and is ordered to receive co-trimoxazole (Bactrim, Septra). The nurse should evaluate for a(n):

Accepted Answer

Co-trimoxazole has hypoglycemic actions.

Question 6

A client is ordered to receive sulfisoxazole (Gantrisin) for chronic otitis media. The medication is ordered 5 mg/kg/dose. The client weighs 132 pounds. The medication is available as 125 mg/5 mL. The nurse should administer how many milliliters for each dose?

Accepted Answer

The answer of A client is ordered to receive sulfisoxazole...

Question 7

Which nursing instruction related to photosensitivity is highest priority for the client receiving a sulfonamide?

Accepted Answer

Using a high SPF sunblock decreases the risk of photosensitive reactions.

Question 8

A client is ordered to take the anticoagulant warfarin (Coumadin) with co-trimoxazole (Bactrim, Septra). Based on the interaction of the drugs, the client's warfarin level should be monitored and the dose may need to be adjusted in which way?

Accepted Answer

Sulfonamides can increase the anticoagulant effects of warfarin.

Question 9

A client is diagnosed with an infection and is ordered to receive a sulfonamide. What would the nurse evaluate as a positive response to the treatment?

Accepted Answer

A body temperature within normal limits indicates that the medication is effective.

Question 10

The client is being treated with one of the sulfonamides. She complains to the nurse of experiencing a sore throat. What is the highest priority action on the part of the nurse?

Accepted Answer

Observe the client for hematologic reaction that may lead to life-threatening anemias. Early signs are sore throat, purpura, and decreasing white blood cell and platelet counts.

Question 11

The client is being treated with Bactrim. The nurse should anticipate seeing an increase in the client's serum:

Accepted Answer

Bactrim will produce an increase in the client's BUN and creatinine levels.

Question 12

A client with a UTI is ordered to receive trimethoprim-sulfamethoxazole, also known as co-trimoxazole (Bactrim, Septra). The nurse is aware that Bactrim is a combination of two drugs. What is the purpose of this combination?

Accepted Answer

Use of sulfonamides leads to bacterial resistance. The trimethoprim prevents this.

Question 13

A client is diagnosed with a urinary tract infection and is ordered to receive 160 mg trimethoprim/200 mg sulfamethoxazole. Based on the physician's order, what is the highest priority nursing intervention?

Accepted Answer

The dosage is inappropriate and should be 160 mg trimethoprim/800 mg sulfamethoxazole.

Quiz 31: Sulfonamides

The client has been ordered treatment with Gantanol. The highest priority instruction to provide this client is:

A client is ordered to receive co-trimoxazole (Bactrim, Septra) . The nurse assesses for side effects. What causes the nurse the greatest concern?