Question 1

Rank the following in order of decreasing basicity (most basic on left): 
A) Z > X > Y
B) Y > X > Z
C) Z > Y > X
D) X > Z > Y
E) X > Y > Z

Accepted Answer

A

Question 2

Which of the following represents N-ethyl-2-phenylethylamine?
A)

B)

C)

D)

E)

Accepted Answer

A

Question 3

Absorptions at 3358 cm^-1 and 3283 cm^-1 in the IR spectrum would suggest which of the following compounds? A) B) C) D) E) cannot tell from the absorption data

Accepted Answer

The two absorptions suggest the presence of a C-H bond, and compound B is the only one with a C-H bond.

Question 4

Which of the molecules below is the strongest base?
A)

B)

C)

D)

E)

Accepted Answer

In this case, the strongest base is the molecule that will most readily accept a proton (H+ ion). This molecule will have the highest tendency to donate a pair of electrons to form a new bond. In molecule C, the lone pair on the nitrogen is present in a sp3 hybrid orbital, which allows for a more stable negative charge on the nitrogen. This makes it easier for the nitrogen to accept a proton and is thus the strongest base.

Question 5

What is the result of the reaction shown? 
A)

B)

C)

D)

E)

Accepted Answer

The answer of What is the result of the reaction...

Question 6

Which of the following reactions can be used to prepare ethylamine?
A)

B)

C)

D)

E) All of the above.

Accepted Answer

The answer of Which of the following reactions can be...

Question 7

What is the structure of lithium diisopropylamide (LDA)?
A)

B)

C)

D)

E)

Accepted Answer

The answer of What is the structure of lithium diisopropylamide...

Question 8

What product would result from the following reaction? A) B) C) D) E)

Accepted Answer

The answer of What product would result from the following...

Question 9

Which of the following sets of reagents would accomplish the reaction shown below? 
A)

B)

C)

D)

E)

Accepted Answer

The answer of Which of the following sets of reagents...

Question 10

What would be formed in the following reaction? A) CH₃NH₂ B) (CH₃)₂NH C) (CH₃)₃N D) None of these. E) All of these.

Accepted Answer

The answer of What would be formed in the following...

Question 11

Which of the following is not formed as either an intermediate along the reaction pathway or as a final product for the Mannich reaction shown below? 
A)

B)

C)

D)

E)

Accepted Answer

Compound 11eab5f7_3d8a_13df_a628_25dae3d90131 is not formed as either an intermediate or final product in the Mannich reaction.

Question 12

Which of the following is not limited to the synthesis of primary amines (R-NH₂ or Ar-NH₂)(i.e.,which,if any,can be used to make 2° or 3° amines)? A) Gabriel synthesis B) Reduction of amides with LAH C) Hofmann rearrangement D) Reduction of nitriles with LAH E) Reduction of nitro groups with Fe/HCl

Accepted Answer

The reduction of amides with lithium aluminum hydride (LAH) can produce primary, secondary, or tertiary amines depending on the structure of the starting amide.

Question 13

What product would result from the Hofmann elimination of the following quaternary ammonium hydroxide? 
A)

B)

C)

D)

E)

Accepted Answer

The answer of What product would result from the Hofmann...

Question 14

Predict the major organic product of the following reaction. 
A)

B)

C)

D)

E)

Accepted Answer

The answer of Predict the major organic product of the...

Question 15

Which of the following products would you expect to result from the following reactions? 
A)

B)

C)

D)

E)

Accepted Answer

The answer of Which of the following products would you...

Question 16

Which of the following structures is a secondary amine?
A)

B)

C)

D)

E)

Accepted Answer

The answer of Which of the following structures is a...

Question 17

What by-product(s)would you expect to contaminate methyl amine prepared by the following reaction? A) (CH₃)₂NH B) (CH₃)₃N C) (CH₃)₄N⁺ I^- D) All of the above. E) None of the above.

Accepted Answer

All three by-products [(CH₃)₃N, (CH₃)₄N⁺ I^-, (CH₃)₂NH] contain a nitrogen atom and are likely to contaminate the methyl amine product.

Question 18

N-nitrosoamines (called nitrosamines)have what outstanding characteristic?
A) An intense fishy odor
B) Tend to be carcinogenic
C) Ammonia-like odor
D) Easily rearrange
E) Have acidic N-H hydrogens

Accepted Answer

Nitrosamines are known to be carcinogenic and can be formed from certain dietary sources such as processed meats that contain nitrite preservatives.

Question 19

What major product would you expect from the reaction shown? 
A)

B)

C)

D)

E)

Accepted Answer

The reaction shown is a substitution reaction between a bromine atom and a hydroxyl group. The product would be a compound where the bromine replaces the hydroxyl group. Among the options given, only option B has the correct placement of the bromine atom. Option A shows the bromine atom in the wrong position, option C shows an additional carbon atom, option D shows two bromine atoms, and option E shows a completely different compound with a different functional group. Therefore, the best choice is B.

Question 20

What process accomplishes the following transformation? 
A) Gabriel synthesis
B) Hofmann rearrangement
C) Reductive amination
D) Mannich reaction
E) Hofmann elimination

Accepted Answer

The answer of What process accomplishes the following transformation? 
A)...

Quiz 21: Amines and Their Derivatives: Functional Groups Containing Nitrogen

Rank the following in order of decreasing basicity (most basic on left) :

Which of the following represents N-ethyl-2-phenylethylamine?

Absorptions at 3358 cm^-1 and 3283 cm^-1 in the IR spectrum would suggest which of the following compounds?

Which of the molecules below is the strongest base?

What is the result of the reaction shown?

Which of the following reactions can be used to prepare ethylamine?

What is the structure of lithium diisopropylamide (LDA) ?

What product would result from the following reaction?

Which of the following sets of reagents would accomplish the reaction shown below?

What would be formed in the following reaction?

Which of the following is not formed as either an intermediate along the reaction pathway or as a final product for the Mannich reaction shown below?

Which of the following is not limited to the synthesis of primary amines (R-NH₂ or Ar-NH₂) (i.e.,which,if any,can be used to make 2° or 3° amines) ?

What product would result from the Hofmann elimination of the following quaternary ammonium hydroxide?

Predict the major organic product of the following reaction.

Which of the following products would you expect to result from the following reactions?

Which of the following structures is a secondary amine?

What by-product(s) would you expect to contaminate methyl amine prepared by the following reaction?

N-nitrosoamines (called nitrosamines) have what outstanding characteristic?

What major product would you expect from the reaction shown?

What process accomplishes the following transformation?