Surprisingly, nasal axons mistarget along the A-P axis in ephrin-A5 knockout mice. In which cells is ephrin-A5 necessary for normal nasal axon targeting?
A) In the posterior tectum, via forward signaling
B) In the anterior tectum, via forward signaling
C) In the nasal RGC axons, via reverse signaling
D) In the nasal RGC axons, via forward signaling
E) In the temporal RGC axons, via reverse signaling

Question

Quizplus · Accepted Answer

Ephrin-A5 is expressed in the nasal RGC axons, and its reverse signaling is necessary for normal nasal axon targeting.

Surprisingly, Nasal Axons Mistarget Along the A-P Axis in Ephrin-A5