Roughly half of the projection neurons generated by the dorsal neuroblast are Caps⁺ and roughly half are Caps^-. Based on this information and the pattern of Caps expression in projection neurons and their glomerular targets in flies: A) Caps level governs glomerular targeting along the dorsolateral-ventromedial axis. B) Caps level governs glomerular targeting along the anteroposterior axis. C) Caps level segregates dendrites that have targeted to similar positions along the axes. D) Caps level depends on neuroblast lineage. E) All of the above

Question

Quizplus · Accepted Answer

Caps expression has a salt-and-pepper pattern rather than being organized in a gradient along one of the axes of the antennal lobe. It does not appear to depend on neuroblast lineage since dorsal neuroblast progeny can be either Caps⁺ or Caps^-. Instead, Caps⁺ dendrites target specific glomeruli while Caps^- dendrites target a non-overlapping set of glomeruli.

Roughly Half of the Projection Neurons Generated by the Dorsal