Which one of the following activities would LEAST likely be found in a topoisomerase?
A)cutting a phosphodiester linkage
B)inducing or relaxing twists in double-stranded DNA
C)adding nucleotides to the end of a DNA strand
D)reforming phosphodiester linkages
E)Topoisomerases are equally likely to perform all of these functions.

Question

Quizplus · Accepted Answer

Topoisomerases are enzymes that are involved in the regulation of DNA supercoiling. They can relax or induce twists in double-stranded DNA, cut phosphodiester linkages, and reform them. However, they do not add nucleotides to the end of a DNA strand, so choice C would be the least likely activity found in a topoisomerase.

Which One of the Following Activities Would LEAST Likely Be