Imagine That You and Your Colleagues Are Working in a Lab

Imagine that you and your colleagues are working in a lab to develop a protein synthesis system for a new type of synthetic cell. During your brainstorming sessions, you propose that polycistronic mRNA (an mRNA with multiple start and stop codons) would be much more useful than mRNA that is only translated into one protein (with just one start and stop codon). This would allow for multiple proteins necessary for a particular function to be translated together. One of your colleagues says that is a good idea, but if you decide to go with polycistronic mRNA, you'd better make sure to use a prokaryotic translation system. Why might it be problematic to use a eukaryotic translation system with polycistronic mRNA?