Many diseases are the result of a problem with cell signaling. Which of the following diseases BEST exemplifies this fact?
A)cystic fibrosis, which is caused by a mutation in a channel protein, resulting in a buildup of mucus
B)congestive heart failure, which is caused by chronic high blood pressure due to excessive sodium intake
C)a specific type of cancer, which is caused by a truncated receptor that becomes stuck in the activated for.
D)familial hypercholesterolemia (high cholesterol in the blood), which is caused by a decrease in the number of receptors for cholesterol.

Question

Quizplus · Accepted Answer

Cancer cells often have mutations in cell signaling pathways, including receptors and their downstream effectors. A truncated receptor that becomes stuck in the activated form would result in constant signaling, leading to uncontrolled cell growth and division. The other options involve problems with membrane transport (cystic fibrosis), cardiovascular function (congestive heart failure), or receptor function (familial hypercholesterolemia), but are not caused specifically by cell signaling abnormalities.

Many Diseases Are the Result of a Problem with Cell