Which of the following is true when there is a single substituent on cyclohexane?
A) This substituent will prefer to be in the axial position.
B) This substituent will prefer to be in the equatorial position.
C) This substituent has no particular preference for either the axial or equatorial position.
D) The situation will vary, depending on the identity of the substituent.

Question

Quizplus · Accepted Answer

When there is a single substituent on cyclohexane, it will prefer to be in the equatorial position to minimize steric hindrance. The axial position places the substituent in close proximity to the other axial atoms, leading to increased steric hindrance. This preference for the equatorial position is true for most common substituents.

Which of the Following Is True When There Is a Single