What would happen to the resting potential of a neuron if the sodium ion channels on a membrane were permanently closed (i.e.,unable to open)?
A) It would constantly fire action potentials.
B) It would have a longer refractory period after an action potential.
C) It would be hyperpolarized.
D) It would have a higher threshold of activation.

Question

Quizplus · Accepted Answer

The resting potential of a neuron is maintained by the balance of electrical charges across the cell membrane. Sodium ions have a positive charge and their influx into the cell during depolarization leads to a reduction in the negative charge inside the cell, making it more likely to generate an action potential. If the sodium ion channels were permanently closed, the cell would have fewer positively charged ions entering, causing the cell to become more negative inside. This leads to hyperpolarization, making it more difficult for the neuron to generate an action potential.

What Would Happen to the Resting Potential of a Neuron