What is the CORRECT order for the following members of the MAP Kinase cascade? 1) MEK
2) ERK
3) Raf
4) RTK
A) 4, 2, 3, 1
B) 2, 1, 3, 4
C) 4, 3, 1, 2
D) 4, 1, 2, 3
E) 4, 3, 2, 1

Question

Quizplus · Accepted Answer

The MAP kinase cascade is initiated by receptor tyrosine kinase (RTK) activation. Subsequently, the activated RTK recruits and activates Raf kinase, which then activates MEK. Finally, activated MEK phosphorylates and activates ERK. Therefore, the correct order is 4, 3, 1, 2, which corresponds to choice C.

What Is the CORRECT Order for the Following Members of the MAP