Which metabolic effect is associated with AMP-activated protein kinase (AMPK)?
A) When activated, AMPK stimulates insulin release from the pancreas.
B) When activated, AMPK activates fructose 2,6-bisphosphatase.
C) When activated, AMPK stimulates glucose uptake in cardiac and skeletal muscle.
D) When activated, AMPK both activates fructose 2,6-bisphosphatase and stimulates glucose uptake in cardiac and skeletal muscle.
E) None of the answers is correct.

Question

Quizplus · Accepted Answer

When activated, AMPK stimulates glucose uptake in cardiac and skeletal muscle. This is because AMPK helps to increase the number of glucose transporters present in the cell membrane, allowing for more glucose uptake and utilization by the muscle cells. AMPK does not stimulate insulin release from the pancreas (A) and does not activate fructose 2,6-bisphosphatase (B). D is incorrect because AMPK only activates glucose uptake, not fructose 2,6-bisphosphatase.

Which Metabolic Effect Is Associated with AMP-Activated Protein Kinase (AMPK)