Which groups act as nucleophiles in the splicing of group I introns?
A) 2' OH groups only
B) 3' OH groups only
C) 5´ OH groups only
D) both 2' and 5'OH groups
E) both 3'and 5' OH groups

Question

Quizplus · Accepted Answer

The correct nucleophiles in the splicing of group I introns are both the 3' OH groups and the 5' OH groups. These groups participate in the splicing mechanism by attacking the phosphate backbone at specific sites, facilitating the removal of the intron and the ligation of the exons.

Which Groups Act as Nucleophiles in the Splicing of Group