Triple-helical DNA structures can result from Hoogsteen (non Watson-Crick) interactions. These interactions are primarily:
A) covalent bonds involving deoxyribose.
B) covalent bonds involving the bases.
C) hydrogen bonds involving deoxyribose.
D) hydrogen bonds involving the bases.
E) hydrophobic interactions involving the bases.

Question

Quizplus · Accepted Answer

Hoogsteen interactions occur when the purine base in one strand of DNA forms hydrogen bonds with the pyrimidine base in another strand, resulting in a non-Watson-Crick base pairing. Therefore, the interactions involved in triple-helical DNA structures are primarily hydrogen bonds between the bases.

Triple-Helical DNA Structures Can Result from Hoogsteen (Non Watson-Crick) Interactions