You identify a cell in which DNA polymerase III is functional, but it seems to exhibit extremely low processivity. This is likely a defect in what structure?
A)the t proteins
B)the pol III holoenzyme
C)the clamp loader
D)the topoisomerase enzyme
E)the sliding clamp

Question

Quizplus · Accepted Answer

The sliding clamp is responsible for maintaining high processivity of DNA polymerase III. If there is a defect in the sliding clamp, processivity will be decreased, as observed in this scenario. The other structures listed are important for DNA replication, but are not specifically responsible for maintaining processivity.

You Identify a Cell in Which DNA Polymerase III Is