What is the consequence of methylation of DNA sequence called CpG islands?
A)Active transcription
B)Transcription repression
C)Recruitment of chromosome remodeling complex
D)Transcriptional stalling
E)Insulator sequence formation

Question

Quizplus · Accepted Answer

Methylation of DNA sequence called CpG islands causes transcription repression. The addition of a methyl group to the cytosine residue within the CpG dinucleotide inhibits the binding of transcription factors and attracts proteins that silence gene expression, leading to an overall decrease in gene expression.

What Is the Consequence of Methylation of DNA Sequence Called